于贤勇, 男, 1975年8月出生, 博士后, 教授, 硕士生导师, 湖南省新世纪“121人才工程”人选（第三层次）, 湖南省青年骨干教师。理论有机化学与功能分子教育部重点实验室专职研究人员, 从事配位化学和精细有机合成化学研究。先后主持国家基金1项目, 中国博士后基金1项, 湖南省自然科学基金2项, 湖南省教育厅重点项目1项, 高校创新平台开放基金1项目, 横向课题8项, 参与国家自然科学基金和其它省部级项目6项。指导研究生主持湖南省研究生创新基金1项、湖南科技大学研究生创新基金2项。在Dalton Trans.、J. Org. Chem.、Inter. J. Mass Spectr.、Spectrochim. Acta A、J. Coord. Chem.等国内外权威刊物发表SCI文章100余篇, 授权专利5项。10年来论文被引约为1000余次。

联系方式：512098818@qq.com，yu_xianyong@163.com

主持项目:

4. 粘蛋白特异性识别的抗肿瘤糖肽基过氧钒配合物的设计与合成, 湖南省自然科学基金

(14JJ7049), 2014.1 - 2016.12, 1万

5. 一种优化的依达拉奉合成方法, 专利转让, 辽宁远大制药, 2015年, 5万

7. 盐酸二甲双胍的合成工艺开发, 横向课题(北京格林富诚科技), 2014年, 5万

8. 双过氧钒钾盐配合物及制备方法、单晶培养, 专利转让, 湘潭开元化学, 2013年, 5万

9. 一种双过氧钒配合物及制备方法、单晶培养, 专利转让, 天津特安化学, 2012年, 5万

10. 高活性过氧钒化合物的合成与快速筛选, 国家自然科学青年基金(20803020), 2009.1 –

2011.12, 18万

兼职工作

2020.4 – 2022.12, 湖南九典制药股份有限公司国家级企业技术中心专家委员会专家

2019.1 - 现在, 湖南省化学化工学会精细化工委员会委员

2018.8 - 现在, 精细化工中间体期刊编委，优秀审稿人

SCI论文:

1. R. X. Chen, X. Y. Yu*, J. F. Dai, K. Q. Deng*, S. W. Zhang*, Crystal structure and DNA cleavage properties of

a vanadium complex [NH4][VO(O2)2(pm-im)]⋅3H2O containing 2-(1H-imidazol-2-yl)pyrimidine ligand. J. Coord. Chem., 2022, 75(1-2), 49-60.

2. Z. J. Yi, J. T. Sun, T. Y. Yang, X. Y. Yu*, X. L. Han*, B. G. Wei. Cu(OTf)2-catalyzed C3 aza-Friedel–Crafts

alkylation of indoles with N,O-acetals, Org. Biomol. Chem., 2022, 20, 2261-2270.

3. Z. J. Yi, Q. Deng, X. Y. Yu*, R. X. Chen, X. F. Li*. NMR and theoretical study on the linking properties of peroxovanadium(V) complexes with the 2-acylpyridine derivatives. J. Coord. Chem., 2020, 73(16), 2301-2310.

4. X. J. Chen, Q. W. Gui, R. N. Yi, X. Y. Yu*, Z. L. Wu, Y. Huang, Z. Cao, W. M. He*. Copper(I)-catalyzed intermolecular cyanoarylation of alkenes: convenient access to alpha-alkylated arylacetonitriles. Org. Biomol. Chem., 2020, 18(27), 5234-5237.

5. Y. X. Tang, Y. J. Yu, X. Y. Wei, J. Yang, Y. T. Zhu, Y. H. Zhao*, Z. L. Tang, Z. H. Zhou, X. F. Li, X. Y. Yu*. An efficient approach to isoquinoline via AgNO3-promoted 6-endo-dig cyclization followed by oxidative elimination of o-alkynylarylaldimines and its application in fluoride recognition. Tetrahedron Lett., 2019, 60(43), 151187.

6. M. Sun, J. Jiang*, J. L. Chen, Q. Yang, X. Y. Yu*. Deep eutectic solvent promoted hydrothiocyanation of alkynoates leading to Z-3-thiocyanatoacrylates. Tetrahedron, 2019, 75(34), 130456.

7. M. Sun, S. W. Zhang*, J. Zhang, X. Wen, J. L. Chen, X. Y. Yu*. Crystal structure and catalytic property of a vanadium complex cis-[VO2(Him-py)(im-py)]2∙3H2O. J. Coord. Chem., 2019, 72(11), 1899-1909.

8. P. Chen, S. W Zhang*, J. Zhang, W. Xia, X. Y. Yu*. J. Coord. Chem., 2019, 72(2), 239-250.

9. X. J. Chen, P. Chen, J. Zhang, S. W. Zhang, X. Y. Yu*, X. F. Li*. NMR study on the coordination of diperoxovanadium(V) complexes with 2-hydroxymethyl pyridine derivatives. J. Coord. Chem., 2019, 71(19), 3117-3126.

10. D. M. Ren, Y. Tang, X. Y. Yu*, Y. L. Huang, X. F. Li. Synthesis of spiro cyclopent-2/3-ene-1,2'-1,3 thiazolo 3,2-a pyrimidine derivatives via 1,3-dipolar cycloaddition reaction of ethyl buta-2,3-dienoate. J. Chem. Res., 2018, 631-635.

11. D. M. Ren, J. Y. Lei, X. Y. Yu*, Y. L. Huang, X. F. Li. Synthesis of 2-(1-oxo-2,3-dihydro-1H-pyrrolizin-2-yl)-2-(aryl)acetonitrile derivatives via Michael addition of trimethylsilyl cyanide. J. Chem. Res., 2018, (9), 467-470.

12. D. M. Ren, J. Y. Lei, X. Y. Yu*, Y. L. Huang, X. F. Li. Synthesis of 4-aryl-3,4,5,6-tetrahydropyrimido 5,4-g indolizine-2(1H)-thione. J. Chem. Res., 2018, 628-630.

13. S. W. Zhang, W. Xia, Y. Y. Yang, X. Y. Yu*, X. F. Li*. Crystal structure and NMR study of a bisperoxovanadium complex NH4VO(O-2)2(ima). J. Coord. Chem., 2017, 70(17), 2958-2968.

14. S. W. Zhang, H. J. Chen, H. J. Tian, X. F. Li, X. Y. Yu*. A 3D supramolecular network constructed from cluster and benzotriazole. Inorg. Chem. Commun., 2017, 86, 87-89.

15. C. F. Xun, Y. C. Wan, X. Y. Yu*, L. Yang, X. F. Li*. Influences of urea on the interaction of 32-Norcorrole with bovine serum albumin. Spectrosc. Lett., 2017, 50(6), 322-329.

16. W. Xia, J. Zhang, X. Y. Yu*, L. Yang, X. F. Li*. NMR and theoretical study on the linking properties of peroxovanadium(V) complexes with the 3-aminomethyl-pyridine derivatives. J. Coord. Chem., 2017, 70(11), 1882-1892.

17. X. Y. Yu*, B. F. Jiang, C. F. Xun, Q. Yao. Interaction between fasudil hydrochloride and bovine serum albumin: spectroscopic study. Luminescence, 2016, 31(4), 986-991.

18. L. L. Yang, X. F. Li*, X. L. Hu, X. Y. Yu*. Simple and efficient synthesis of pyrazole-fused porphyrins. Tetrahedron Lett., 2016, 57(11), 1265-1267.

19. C. F. Xun, X. Y. Yu*, Y. Jiao, B. F. Jiang, X. F. Li*. Interaction between varenicline tartrate and bovine serum albumin. Spectrosc. Lett., 2016, 49(4), 304-310.

20. X. Y. Yu*, Z. X. Liao, B. F. Jiarig, X. L. Hu, X. F. Li*. Spectroscopic analyses on interaction of bovine serum albumin with novel spiro cyclopropane-pyrrolizin. Spectrochim. Acta A, 2015, 137, 129-136.

21. X. Y. Yu*, B. F. Jiang, Z. X. Liao, X. F. Li*. Study on the interaction between 21-(Ph-N=N)-NCTPP and bovine serum albumin by spectroscopic techniques. Spectrochim. Acta A, 2015, 142, 260-265.

22. X. Y. Yu*, B. F. Jiang, Z. X. Liao, Y. Jiao, P. G. Yi*. Study on the interaction between Besifloxacin and bovine serum albumin by spectroscopic techniques. Spectrochim. Acta A, 2015, 149, 116-121.

23. X. Y. Yu*, Z. X. Liao, Q. Yao, H. T. Liu, W. L. Xie*. Spectroscopic studies on the interaction of Phacolysin and bovine serum albumin. Spectrochim. Acta A, 2014, 127, 231-236.

24. X. Y. Yu*, Z. X. Liao, Q. Yao, H. T. Liu, X. F. Li, P. G. Yi*. The investigation of the interaction between Tropicamide and bovine serum albumin by spectroscopic methods. Spectrochim. Acta A, 2014, 118, 331-336.

25. X. Y. Yu*, Z. X. Liao, B. F. Jiang, L. Y. Zheng, X. F. Li*. Study on the interaction between carbonyl-fused N-confused porphyrin and bovine serum albumin by spectroscopic techniques. Spectrochim. Acta A, 2014, 133, 372-377.

26. X. Y. Yu*, L. Deng, B. S. Zheng, B. R. Zeng, P. G. Yi*, X. Xu*. A spectroscopic study on the coordination and solution structures of the interaction systems between biperoxidovanadate complexes and the pyrazolylpyridine-like ligands. Dalton Trans., 2014, 43(4), 1524-1533.

27. X. Y. Yu*, L. Deng, H. W. Tao, B. F. Jiang, X. F. Li*. NMR and theoretical study on the coordination interaction between peroxovanadium(V) complexes and 5-amino-1,10-phenanthroline. J. Coord. Chem., 2014, 67(2), 315-322.

28. Z. X. Liao, X. Y. Yu*, Q. Yao, P. G. Yi*. Interaction between pirenoxine and bovine serum albumin in aqueous solution. Spectrochim. Acta A, 2014, 129, 314-319.

29. B. S. Zheng*, H. T. Liu, Z. X. Wang, X. Y. Yu*, P. G. Yi, J. F. Bai*. Porous NbO-type metal-organic framework with inserted acylamide groups exhibiting highly selective CO2 capture. Crystengcomm, 2013, 15(18), 3517-3520.

30. B. S. Zheng, L. Deng, H. T. Liu, X. Y. Yu*, Z. X. Wang, X. C. Yang, P. G. Yi*. NMR and theoretical study on the coordination interactions between peroxovanadium(V) complex and bisubstituted pyridine ligands. J. Coord. Chem., 2013, 66(14), 2558-2566.

31. X. Y. Yu*, Q. Yao, H. W. Tao, Y. Yang, L. Li, B. S. Zheng*, S. Z. Zhu. A study on the interaction between 3-spiro-piperidones and bovine serum albumin using spectroscopic approaches. Luminescence, 2013, 28(5), 705-712.

32. X. Y. Yu*, Q. Yao, H. W. Tao, Y. Yang, L. Li, X. F. Li*, S. Z. Zhu. Spectroscopic studies on the interaction of BSA and 5-spiro-3'-piperidine-2''-spiro-3''-indole-4',2''-diones. Spectrochim. Acta A, 2013, 104, 519-526.

33. X. Y. Yu*, H. T. Liu, Y. Yang, S. Y. Lu, Q. Yao, P. G. Yi*. The investigation of the interaction between Oxymetazoline hydrochloride and mucin by spectroscopic approaches. Spectrochim. Acta A, 2013, 103, 125-129.

34. Q. Yao, X. Y. Yu*, T. Y. Zheng, H. T. Liu, Y. Yang, P. G. Yi*. Spectroscopic studies on the interaction of carteolol hydrochloride and urea-induced bovine serum albumin. Spectrochim. Acta A, 2013, 113, 447-451.

35. Y. Yang, X. Y. Yu*, W. H. Tong, S. Y. Lu, H. T. Liu, Q. Yao, H. Zhou*. Investigation of the Interaction Between Novel Spiro Thiazolo 3,2-a 1,3,5 Triazines and Bovine Serum Albumin by Spectroscopic Methods. J. Solution. Chem., 2013, 42(3), 666-675.

36. Z. X. Wang, B. S. Zheng*, H. T. Liu, P. G. Yi, X. F. Li, X. Y. Yu*, R. R. Yun*. A highly porous 4,4-paddlewheel-connected NbO-type metal-organic framework with a large gas-uptake capacity. Dalton Trans., 2013, 42(31), 11304-11311.

37. B. Liu, X. F. Li*, H. C. Liu, X. Y. Yu*. Unexpected nitrilimine cycloaddition of thiazolo 3,2-a pyrimidine derivatives. Tetrahedron Lett., 2013, 54(50), 6952-6954.

38. X. Y. Yu, P. G. Yi, D. H. Ji, B. R. Zeng, X. F. Li*, X. Xu*. Study of the coordination and solution structures for the interaction systems between diperoxidovanadate complexes and 4-(pyridin-2-yl)pyrimidine-like ligands. Dalton Trans., 2012, 41(13), 3684-3694.

39. X. Y. Yu, Q. Yao, W. Li, X. C. Liao, Y. Yang, H. T. Liu, X. F. Li*, P. G. Yi*. Investigation of the Interaction Between N-benzyl Piperidones and Bovine Serum Albumin by Spectroscopic Approaches. J. Solution. Chem., 2012, 41(10), 1747-1758.

40. X. Y. Yu, Y. Yang, X. Zou, H. W. Tao, Y. L. Ling, Y. Qing, H. Zhou*, P. G. Yi*. Study on the interaction between novel spiro pyrrolidine and bovine serum albumin by spectroscopic techniques. Spectrochim. Acta A, 2012, 94, 23-29.

41. X. Y. Yu, Y. Yang, Q. Yao, H. W. Tao, S. Y. Lu, J. Xie, H. Zhou*, P. G. Yi*. Spectroscopic analysis of the interaction between thiazolo 2,3-b pyrimidine analogues and bovine serum albumin. Spectrochim. Acta A, 2012, 96, 690-697.

42. X. Y. Yu, S. Y. Lu, Y. Yang, X. F. Li*, P. G. Yi*. Study on the interaction between NCP-(4-hydroxycoumarins) and bovine serum albumin by spectroscopic techniques. Spectrochim. Acta A, 2012, 91, 113-117.

43. S. Y. Lu, X. Y. Yu*, Y. Yang, X. F. Li*. Spectroscopic investigation on the intermolecular interaction between N-confused porphyrins-(3-methylisoxazole) diad and bovine serum albumin. Spectrochim. Acta A, 2012, 99, 116-121.

44. X. Y. Yu, Y. Yang, S. Y. Lu, Q. Yao, H. T. Liu, X. F. Li*, P. G. Yi*. The fluorescence spectroscopic study on the interaction between imidazo 2,1-b thiazole analogues and bovine serum albumin. Spectrochim. Acta A, 2011, 83(1), 322-328.

45. X. Y. Yu, Y. Yang, R. H. Liu, H. W. Huang, J. Chen, D. H. Ji, X. F. Li*, F. X. Yang, P. G. Yi*. The investigation of the interaction between edaravone and bovine serum albumin by spectroscopic approaches. J. Lumin., 2011, 131(7), 1510-1514.

46. X. Y. Yu, R. H. Liu, R. Q. Yi, F. X. Yang, H. W. Huang, J. Chen, D. H. Ji, Y. Yang, X. F. Li*, P. G. Yi*. Study of the interaction between N-confused porphyrin and bovine serum albumin by fluorescence spectroscopy. Spectrochim. Acta A, 2011, 78(4), 1329-1335.

47. X. Y. Yu, R. H. Liu, F. X. Yang, D. H. Ji, X. F. Li, J. A. Chen, H. W. Huang, P. G. Yi*. Study on the interaction between dihydromyricetin and bovine serum albumin by spectroscopic techniques. J. Mol. Struct., 2011, 985(2-3), 407-412.

48. X. Y. Yu, R. H. Liu, D. H. Ji, F. X. Yang, X. F. Li*, J. Xie, J. M. Zhou, P. G. Yi*. Study on the Synergism Effect of Lomefloxacin and Ofloxacin for Bovine Serum Albumin in Solution by Spectroscopic Techniques. J. Solution. Chem., 2011, 40(3), 521-531.

49. R. H. Liu, X. Y. Yu*, W. Gao, D. H. Ji, F. X. Yang, X. F. Li, J. Chen, H. W. Tao, H. W. Huang, P. G. Yi*. Study on the interaction between salvianic acid A sodium and bovine serum albumin by spectroscopic methods. Spectrochim. Acta A, 2011, 78(5), 1535-1539.

50. X. F. Li, H. C. Liu, A. T. Zheng, X. Y. Yu*, P. G. Yi*. Progress in the Syntheses of N-Confused Porphyrins and Their Derivatives. Chinese. J. Org. Chem., 2011, 31(2), 166-175.

51. X. F. Li, H. C. Liu, A. T. Zheng, Z. K. Li, G. B. Li, X. Y. Yu*, P. G. Yi*. Synthesis of Novel Spiro Thiazolo 3,2-a 1,3,5 triazines via 1,3-Dipolar Cycloaddition of Azomethine Ylide. Chinese. J. Chem., 2011, 29(1), 97-101.

52. X. F. Li, B. Liu, P. G. Yi, R. Q. Yi, X. Y. Yu*, P. J. Chmielewski*. Synthesis of N-Confused Porphyrin Derivatives with a Substituted 3-C Position. J. Org. Chem., 2011, 76(7), 2345-2349.

53. Z. H. Hou*, N. B. Zhou, B. H. He, Y. Yang, X. Y. Yu*. Study on the interaction between thiazolopyrimidine analogues and bovine serum albumin. Spectrochim. Acta A, 2011, 79(5), 1931-1935.

54. Z. H. Hou*, N. B. Zhou, B. H. He, Y. Yang, X. Y. Yu*. Study of the interaction between quinocetone and bovine serum albumin by spectroscopic approaches. J. Mol. Struct., 2011, 1004(1-3), 116-120.

55. J. Zhang, X. Y. Yu*, P. G. Yi, H. W. Huang, S. H. Cai, Z. Chen*. Multinuclear NMR and theoretical investigation on interactions between diperoxovanadate complex and 4-picoline-like ligands. Spectrochim. Acta A, 2010, 75(1), 83-87.

56. R. J. Zeng, Z. X. Wang, X. F. Li*, J. Xie, X. Y. Yu*. NMR studies on interactions between diperoxovanadate and picolinamide-like ligands. J. Coord. Chem., 2010, 63(3), 498-504.

57. X. Y. Yu, F. X. Yang, D. H. Ji, J. M. Zhou, R. H. Liu, G. B. Li, X. F. Li, J. A. Chen, H. W. Huang, P. G. Yi*. Spectroscopic investigation of the interaction between diperoxovanadate complexes and benzimidazole-like ligands. Spectrochim. Acta A, 2010, 77(4), 816-820.

58. X. Y. Yu, R. H. Liu, H. L. Peng, H. W. Huang, X. F. Li, B. S. Zheng, P. G. Yi*, Z. Chen. NMR and theoretical study on interactions between diperoxovanadate complex and pyrazole-like ligands. Spectrochim. Acta A, 2010, 75(3), 1095-1099.

59. X. Y. Yu, R. H. Liu, D. H. Ji, J. A. Xie, F. X. Yang, X. F. Li, H. W. Huang, P. G. Yi*. Spectroscopic studies on the interactions between 3,4-dihydropyrimidin-2(1H)-ones and bovine serum albumin. Spectrochim. Acta A, 2010, 77(1), 213-218.

60. X. Y. Yu, D. H. Ji, R. H. Liu, F. X. Yang, J. Xie, J. M. Zhou, X. F. Li, P. G. Yi*. NMR and theoretical study on the interaction between diperoxovanadate and 3-picoline derivatives. J. Coord. Chem., 2010, 63(9), 1555-1562.

61. X. Y. Yu, D. H. Ji, R. H. Liu, H. W. Huang, X. F. Li, B. S. Zheng, Z. X. Wang, P. G. Yi*. NMR Studies on Interactions between Diperoxovanadate Complex and Pyridine-Like Ligands. Chin. J. Inorg. Chem., 2010, 26(4), 639-644.

62. R. J. Zeng, Z. C. Zhou, Z. X. Wang, X. F. Li*, Z. Chen, X. Y. Yu*. Synthesis of Novel Thiazolo 3,2-a pyrimidine Compounds. Chin. J. Org. Chem., 2009, 29(3), 470-475.

63. X. Y. Yu, J. Zhang, S. H. Cai, P. G. Yi, Z. Chen*. Investigation on the complex of diperoxovanadate with picolinamide. Spectrochim. Acta A, 2009, 72(5), 965-969.

64. X. Y. Yu, H. L. Peng, H. W. Huang, Z. X. Wang, B. S. Zheng, X. F. Li, P. G. Yi*, Z. Chen. NMR Studies on Interactions between Diperoxovanadate and 1-Ethyl-1H-Imidazole. Acta Phys-Chim. Sin., 2009, 25(9), 1779-1784.

65. X. Y. Yu, J. Zhang, B. R. Zeng, P. G. Yi, S. H. Cai, Z. Chen*. NMR and theoretical study on interactions between diperoxovanadate complex and 4-substituted pyridines. Spectrochim. Acta A, 2008, 71(2), 644-649.

66. X. Y. Yu, J. Zhang, P. G. Yi*, H. L. Peng, B. S. Zheng, H. W. Huang, Z. Chen. NMR and Theoretical Study on Interactions between Diperoxovanadate Complex and Substituted Pyridines. Acta Chim. Sin., 2008, 66(22), 2476-2482.

67. X. Y. Yu, X. Xu*, Z. Chen*. ESI-MS and theoretical study on the coordination structures and reaction modes of the diperoxovanadate complexes containing histidine-like ligands. Int. J. Mass. Spectrom., 2008, 269(1-2), 138-144.

授权专利