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黄昊文教授简介

时间:2015-12-05 16:35:40 点击:
 

黄昊文,男,1969年生,博士,教授,研究生导师,毕业于中国科学院化学研究所。主要从事纳米材料制备与性质、纳米生物传感、可视化检测分析研究。目前主持国家自然科学基金(21375036,湖南省自然科学基金(14JJ7054),湖南省创新平台项目(13K090各一项。已完成国家自然科学基金、湖南省自然科学基金、湖南省教育厅青年项目、国家重点实验室开放课题等多项研究项目。在《Biomaterials》、《Chemical Communications》、《Analytical Chemistry》、《Biosensor and Bioelectronics》等国际刊物上发表科研论文近20篇,影响因子5.0以上的论文超过10篇。2007年以来,主要论文被《Chem. Soc. Rev.》、《Nano Today》、《J. Am. Chem. Soc.》、《Adv. Mater.》等SCI期刊引用近300次,单篇SCI他引最多超50次。已申请国家发明专利13项(其中已授权7项),获湖南省第12届自然科学优秀学术论文一等奖一项。

研究方向

1、纳米材料的制备及性质研究

2、纳米化学/生物传感器的构建与应用

3、高灵敏度可视化检测

主持科研项目

n 国家自然科学基金项目:可控纳米结构表面等离子体共振生物传感器的构建及肝癌早期检测研究(21375036),2014.01-2017.12

n 湖南省自然科学基金项目:可控金纳米复合结构表面等离子体共振生物传感器的构建研究(14JJ70054), 2014.01-2016.12;

n 湖南省高校创新平台开放基金项目:基于金纳米棒的一维自组装及解组装构建生物传感方法研究(13K090), 2014.01-2016.12;

n 国家自然科学基金项目:核壳型纳米棒构建生物传感器阵列的研究(21075035),2011.01-2013.12

n 湖南省自然科学基金项目:壳层包覆金纳米棒的生物传感器研制与应用(10JJ5004),  2010.01-2012.12;

n 高性能陶瓷和超微结构国家重点实验室开放课题:核壳型纳米棒构建生物传感器的研究(SKL201006SIC, 2011.01-2012.12

n 中国科学院特种无机涂层重点实验室开放课题:基于核壳型纳米粒子的表面等离子体共振性质构建多通量表面分析方法的研究(KLICM-2011-09),2012.01-2013.12

n 固体表面物理化学国家重点实验室:基于金纳米棒的表面分析新方法研究钙调神经磷酸酶与药物的相互作用,2008.01-2009.12

n 湖南省教育厅优秀青年项目:新型生物传感器表面等离子体共振成像仪的研制06B28),2007.01-2009.12

参与科研项目

获奖情况

Ø  湖南省第12届自然科学优秀学术论文一等奖

代表性论文

1.  Shenna Chen, Qian Zhao, Lingyang Zhang, Linqian Wang, Yunlong Zeng, Haowen Huang*, “Combined detection of breast cancer biomarkers based on plasmonic sensor of gold nanorods”,  Sensors and Actuators B: Chemical, 2015, 221, 1391-1397.

2.   Shenna Chen, Qian Zhao, Lingyang Zhang, Xiaodong Xia, Haowen Huang*, “Successive detection of glucose and bio-copper in human serum based on a multiplex biosensor of gold nanorods”, Anatlytical Methods, 2015, 7, 1018-1025.

3.  Qian Zhao, Shenna Chen, Lingyang Zhang, Haowen Huang*, “Detection of Fe(III) and bio-copper in human serum based on fluorescent AuAg nanoclusters”, Anatlytical Methods, 2015, 7, 296-300.

4.  Qian Zhao, Shenna Chen, Lingyang Zhang, Haowen Huang* Fengping Liu, Xuanyong Liu*, “Synthesis of biocompatible AuAgS/Ag2S nanoclusters and their applications in photocatalysis and mercury detection”, Journal of Nanoparticle Research, 2014, 16, 2793.

5.   Qian Zhao, Shenna Chen, Lingyang Zhang, Haowen Huang*, Yunlong Zeng, Fengping Liu, “Multiplex sensor for detection of different metal ions based on on–off of fluorescent gold nanoclusters”, Analytica Chimica Acta, 2014, 852, 236-243.

6.  Qian Zhao, Shenna Chen, Haowen Huang*, Lingyang Zhang, Linqian Wang, Fengping Liu, Jian Chen, Yunlong Zeng,a Paul K. Chu*. Colorimetric and ultra-sensitive fluorescence resonance energy transfer determination of H2O2 and glucose by multi-functional Au nanoclusters”, Analyst, 2014 , 139 ,1498-1503.

7.  Shenna Chen, Qian Zhao, Fang Liu, Haowen Huang*, Linqian Wang, Shoujun Yi, Yunlong Zeng, and Yi Chen*. Ultrasensitive determination of copper in complex biological media based on modulation of plasmonic properties of gold nanorods”, Analytical Chemistry, 2013, 85, 9142–9147.

8.   Haowen Huang*, Shenna Chen, Fang Liu, Qian Zhao, Bo Liao, Shoujun Yi, Yunlong Zeng, “Multiplex plasmonic sensor for detection of different metal ions based on single type of gold nanorod”,  Analytical Chemistry, 2013, 85, 2312-2319.

9.   Haowen Huang*, Fang Liu, Shenna Chen, Qian Zhao, Bo Liao, Yunfei Long, Yunlong Zeng, Xiaodong Xia, “Enhanced fluorescence of chitosan based on size change of micelles and application to directly selective detecting Fe3+ in human serum”, Biosensors and Bioelectronics, 2013, 42, 539-544.

10.  Haowen Huang*, Chunhui Li, Caiting Qu, Shaowen Huang, Fang Liu, Yunlong Zeng, “Sensitive detection of DNA based on the optical properties of core–shell gold nanorods”, Journal of Nanoparticle Research, 2012, 14, 754.

11.  Haowen Huang*, Fang Liu, Shaowen Huang, Shishan Yuan, Bo Liao, Shoujun Yi, Yunlong Zeng, Paul K. Chu*, “Sensitive and simultaneous detection of different disease markers using multiplexed gold nanorods”, Analytica Chimica Acta, 2012, 755, 108-114.

12.  Haowen Huang*, Caiting Qu, Xuanyong Liu, Shaowen Huang, Zhongjian Xu, Yingjie Zhu, Paul K. Chu*, “Amplification of localized surface plasmon resonance signals by a gold nanorod assembly and ultra-sensitive detection of mercury”, Chemical Communications, 2011, 47, 6897-6899.

13.  Haowen Huang*, Shaowen Huang, Shishan Yuan, Caiting Qu, Yi Chen, Zhongjian Xu, Bo Liao, Yunlong Zeng, Paul K. Chu*, “High-sensitivity biosensors fabricated by tailoring the localized surface plasmon resonance property of core–shell gold nanorods”, Analytica Chimica Acta, 2011, 683, 242-247.

14.  Haowen Huang*Xuanyong Liu Bo Liao Paul K. Chu, “A localized surface plasmon resonance biosensor based on integrated controllable Au2S/AuAgS-coated gold nanorods composite Plasmonics, 2011, 6, 1-9.

15.  Haowen Huang*, Caiting Qu, Xuangyong Liu, Shaowen Huang, Zhongjian Xu, Bo Liao, Yunlong Zeng, Paul. Chu*, “Preparation of controllable core-shell gold nanoparticles and its application in detection of silver ions”, ACS Applied Materials & Interfaces, 2011, 3, 183-190.

16. Haowen Huang*, Xuanyong Liu, Tao Hu, Paul K. Chu*, “Ultra-sensitive detection of cysteine by gold nanorod assembly”, Biosensor and Bioelectronics, 2010, 25, 2078-2083.

17.  Haowen Huang*, Xuanyong Liu, Yunlong Zeng, Xianyong Yu, Bo Liao, Pinggui Yi, Paul K. Chu*, “Optical and biological sensing capabilities of Au2S/AuAgS coated gold nanorods”, Biomaterials, 2009, 30, 5622-5630.

18. Haowen Huang*, Chaocai He, Yunlong Zeng, Xiaodong Xia, Xianyong Yu, Pinggui Yi, Zhong Chen, “A novel label-free multi-throughput optical biosensor based on localized surface plasmon resonance”, Biosensors and Bioelectronics, 2009, 24, 2255–2259.

19.  Haowen Huang*, Shaowen Huang, Xuanyong Liu, Yunlong Zeng, Xianyong Yu, Bo Liao , Yi Chen*, “Label-free optical biosensors based on Au2S coated gold nanorods”, Biosensors and Bioelectronics, 2009, 24,3025-3029.

20.  Haowen Huang*, Chunran Tang, Yunlong Zeng Xianyong Yu, Bo Liao, Xiaodong Xia, Pinggui Yi, Paul K. Chu*, “Label-free optical biosensor based on localized surface plasmon resonance of immobilized gold nanorods”, Colloids and Surfaces B, 2009, 71, 96-101.

专利

1.    黄昊文,贺超才,曾云龙,夏晓东,连续可调控纵横比的金纳米棒制备方法,发明专利,Zl200710034358.6

2.    黄昊文,贺超才,曾云龙,夏晓东,于贤勇,一种提高金纳米棒的纯度的方法,发明专利,ZL200710034760.4

3.    黄昊文,贺超才,曾云龙,夏晓东,于贤勇,一种可调等离子体波的金纳米棒的制备方法,发明专利,ZL200710035251.3

4.    黄昊文, 屈彩婷, 许中坚,易守军,一种制备核壳型金纳米粒子及用于检测银离子浓度的方法,发明专利,ZL 201010289193.9

5.  黄昊文, 屈彩婷, 许中坚,易守军,廖博,一种基于金纳米棒自组装快速检测汞的方法,发明专利, ZL201110099983.5

6.  黄昊文,陈甚娜,刘芳,赵倩,基于局域表面等离子体性质检测多种金属离子方法及其应用,发明专利,ZL201210554832.9

7.   黄昊文,赵倩,陈甚娜,张凌阳,制备复合硫化银金/硫化银纳米簇的方法及其应用,发明专利,201310675248.3

8.   黄昊文,陈甚娜,赵倩,张凌阳,一种检测葡萄糖和铜的含量的方法及其应用,发明专利公开号,CN104132916A

9.   黄昊文,张凌阳,赵倩,陈甚娜,微波辅助法制备碳点及用于检测钾离子浓度的方法及应用,发明专利公开号,CN104263365A

10. 黄昊文,赵倩,陈甚娜,张凌阳,周媛,刘兰芳,一种基于金纳米簇模拟酶试剂盒及其制备方法及应用,发明专利公开号,CN104502614A

11.  黄昊文,张凌阳,刘兰芳,周媛,双色荧光含金碳点的制备及该碳点在可视化检测的应用,发明专利申请号,201510546606.X

12. 黄昊文,刘兰芳,张凌阳周媛,刘兰芳,张凌阳,一种基于乙二胺四乙酸模拟酶试剂盒的制备方法及其应用,发明专利申请号201510545849.1

13. 黄昊文,张凌阳,刘兰芳,周媛,一种具有催化性能的碳点制备及基于此碳点试剂盒的应用,发明专利申请号,201510545769.6

社会兼职

n 中国化学会会员,国家自然科学基金通信评审专家,《ACS Nano》、《Biomaterials》,《Chemical Communications,Analytical Chemistry》、《Biosensor and Bioelectronics》、《Nanoscale》、《Journal of Materials Chemistry》等多种国际期刊审稿人。



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